Structure and function of the heart

Describe the structure and function of the heart anddelay of 0.1 seconds allows the atria to fully contract
explain how it responds to exercise or disease.  Howand force the blood into the ventricles.  The AV
could you measure this clinically or in the laboratory?Bundle (Bundle of His), then, speeds the impulse rapidly
 through the ventricles over the Purkinje Fibres (fibres
 penetrating the left and right ventricles), causing
The heart is anchored and protected by the pericardialcontraction of the ventricles.
sac.  The pericardium has two layers; the fibrous 
pericardium and the serous pericardium.  These twoStimulation of the sympathetic cardio-accelerator
layers work in conjunction with each other to preventnerves releases neural hormones, such as epinephrine
the heart from over-stretching, thus, preventing overand norepinephrine.  These hormones increase
filling of the heart but also allows for rapid and vigorousmyocardial contractibility by accelerating depolarization
contraction where required.of the SA Node, this increases the heart rate.  The
 parasympathetic nervous system releases hormones,
Between the two pericardial layers is the pericardialsuch as acetylcholine.  These hormones have
cavity which is filled with serous fluid.  This fluidopposite effect on the heart’s activity.  This
contributes to the protection of the heart as it provideschange in neural hormone release occurs when there
lubrication allowing the heart to contract free fromis an increase or decrease in physical activity.
friction. 
  
The heart is made up of three layers; the epicardium,Cardiac output components in endurance-trained and
myocardium and the endocardium. untrained subjects during rest and maximal exercise
  
The heart acts as a dual pump.  The left side of the 
heart pumps blood to and from the lungs, this is theCardiac output (ml)
pulmonary circulation and the blood being distributed byHeart rate (b. Min-1)
the right side of the heart is pumped around the restStroke Volume (ml. B-1)
of the body via the systemic circulation.Untrained
 Rest
Each “pump” consists of atria and ventricles. Maximal Exercise
The atria are located superior to the ventricles and are 
made up of thin, smooth walls covered with5000ml
endothelium.22,000ml
  
The ventricles have thicker muscles than the atria; this70 b. Min-1
allows the ventricles to provide enough force for the195 b. Min-1
blood to be pumped out of the heart to tissues and 
organs.  The walls of the left ventricle are thicker than71 ml. B-1
those of the other chambers; this is due to the greater113 ml. B-1
stress that is being applied.Endurance Trained
 Rest
Between the four chambers are thin partitions held inMaximal Exercise
place by connective tissue, these prevent blood from 
one chamber being contaminated with the blood from5000ml
another.  The interatrial septum separates the atria35,000ml
and the interventricular septum separates the 
ventricles.50 b. Min-1
Valves located in the heart play a vital role in195 b. Min-1
preventing back flow of blood.  The atrioventricular 
valve (tricuspid valve) is found between the right atrium100 ml. B-1
and the right ventricle (Fig. 3); this stops the blood being179 ml. B-1
pumped back in to the atrium as the ventricle 
contracts.Table taken from: McArdle, W. D.et al.  Essentials of
 Exercise Physiology. 2nd Edition. 2000
Between the left atrium and the left ventricle, the mitral 
valve (bicuspid valve) is found; the role of this particularThese changes are achieved as hypertrophy
valve is similar to that of the atrioventricular valve. (increase of muscle fibre) occurs.  Echocardiography
This valve has two lobes; this is due to the highinvolves the use of sound waves to produce an image
pressure and force of contraction from the leftshowing the structure of the heart, including its four
ventricle.chambers and the myocardium structure.  It has been
 used to determine what training types can inflict
When the blood leaves the left ventricle, it enters themyocardium enlargement and whether there are
aorta.  The aortic valve acts as a barrier and doesconsequences to health from hypertrophy due to
not allow the blood to flow back into the heart as thephysical activity. 
ventricle relaxes. 
 During exercise blood pressure and heart rate
It is the Sino-atrial Node (SV Node), the pace maker,increase.  This is due to the demand from working
that intrinsically regulates the heart rate.  The electricmuscles to remove waste (I. e. CO2) in order to keep
pulse then passes across the atria, causing them toperform effectively.
contract, to the Atrio-ventricular Node (AV Node).  A