Breast Cancer - Paget's Disease

One of the rare types of Breast Cancer is Paget'sroutine treatment for eczema or infection and usually
disease of the nipple, which can appear as a rash ononly affects one nipple.A mammogram is the next
the nipple. The rash or other changes in the nipple canstep to check for cancer in the actual breast.
indicate a cancer in the breast ducts, many timesSometimes any underlying abnormal breast mass will
located under the nipple, which has then extended itselfnot be present on a mammogram. A clean
onto the surface of the nipple.Sometimes this sign ofmammogram combined with an abnormal nipple finding
breast cancer indicates a small ductal carcinoma in siturequires further investigation.A biopsy of the nipple
(DCIS), which is a very early breast cancer that hastissue will need to be performed. Usually this consists
not yet left the duct. Other times, Paget's disease ofof a "punch biopsy" that removes a small amount of
the nipple may indicate an invasive cancer somewheretissue to check for cancer. If the mammogram
else in the breast. In some cases, a woman whoindicates other areas of concern within the breast,
shows signs of Paget's disease of the nipple willbiopsies of those areas should be performed.If Paget's
additionally have an abnormal mammogram or havedisease is caught early while it is still confined to the
lump in her breast.Before we move on I want to clarifynipple and underlying breast ducts, the patient typically
that Paget's disease of the nipple is not the same ashas an excellent prognosis. However, if Paget's
Paget's disease of the bone, which is a severe bonedisease of the nipple is associated with an invasive
disease. Sir James Paget, a British surgeon andbreast cancer or if the cancer has spread out of the
physiologist, discovered both conditions which werebreast to other areas of the body (metastatic
first documented by him, but they are completelydisease), the survival rate can be lower.Treatment of
unrelated diseases. Paget's disease of the nipple canPaget's disease of the nipple involves surgery, radiation
also affect men, although it is rare.Paget's disease oftreatment and Chemotherapy or drug therapy (such
the nipple is often first noticed when physical signs ofas tamoxifen). Like other types of breast cancer, the
the disease appear. Signs of Paget's disease usuallylocation of the cancer will determine which type of
only occur on one nipple and can include persistentsurgery is done - a lumpectomy or mastectomy.
crustiness, scaliness, or redness of the nipple, itching orRadiation therapy usually follows a lumpectomy.A
burning of the nipple and surrounding areola andrecent development in surgical treatment involves
bleeding or oozing from the nipple and areola.Paget'sremoving only the nipple and areola (sometimes
disease can often be confused with other skinfollowed by radiation therapy) in patients whose
conditions, such as breast eczema. Breast Eczema isPaget's disease has no other underlying breast cancer,
a highly treatable condition which can be characterizedthus allowing the woman to keep her breast. Following
by red, itchy patches or weeping blisters around thetreatment, an artificial nipple can be recreated using
nipple which reoccur, but clear up with properskin grafts and tattooing.
treatment. Paget's disease does not clear up with