Screening For Common Diseases Using Chromogenic Media

Chromogenic media are used for applications whichmedia are becoming an increasingly common item in
require the detection or enumeration of bacteria andclinics, hospitals and medical laboratories, with testing
other microbiological growth. These media are availablefor nosocomial MRSA and Clostridium being especially
as a granular material or as a powder which containimportant in clinical settings.
enzymes which react chromogenically with differentAn especially important use for this type of media is
types of microorganisms. The exact type of mediafor preliminary screening for common diseases; urinary
chosen is dependent on the sort organisms whosetract infections, for one. These types of infections can
presence is being tested for; the enzymes producedbe quickly tested for at clinics using plated
by the target population react with the substrate,chromogenic media, with Klebsiella, Enterobacter and E.
causing a change of color. With customized incubationcoli among the organisms readily detectible in urine
procedures, the selectivity of the application can besamples.
increased, often allowing for a confirmation of theTesting for bacterial contamination in foodstuffs is
target organism without any need for further testing.another common application where chromogenic
Chromogenic media is a somewhat recenttesting is useful; their ability to determine the presence
development in the life sciences, having first been usedof Staphylococcus aureus, Campylobacter, Salmonella,
in the late 1980s when the possibilities of selectiveE. coli and other coliform bacteria and Listeria can all
detection of microorganisms through chromogenicbe tested for. Specific organisms can also be tested
reactions came to be recognized. This procedure isfor using chromogenic analysis, making this an ideal
often used as a simple test for the presence ormethod of ensuring the safety of the food supply.
absence of a particular microorganism, but along withQuite often, the media must be pre-enriched for at
other materials or by plating the media, they can alsoleast 24 hours in order to allow the target organism to
be used for the quantitative analysis of microbes.reach a high enough population to guarantee that
It is color differentiation of this type of media whichthese microbes will also be present in the chromogenic
gives it an advantage over traditional types of culturemedia when a subsample is taken for analysis.
media. Various types of bacterial colonies can beHowever, this is not always necessary, depending on
quickly identified through the distinctive hue or intensitythe target organism, the type of media used and any
of color that these organisms produce when in contactother particular demands imposed by the application or
with chromogenic media. These media are used forenvironment, whether in water and food testing,
easy identification of pathogenic microorganismsscreening for common infections or prenatal care.
including Candida albicans, Staphylococcus aureus,Chromogenic testing has become a valuable tool for
Streptococcus B (used for screening for perinatalquickly detecting potentially disease causing organisms
Group B Strep in infants) and all serotypes ofand given the increase in dangerous antibiotic resistant
Salmonella.microorganisms, is certain to take on an even larger
Due to the increase infections acquired in medicalrole in medicine and the environmental sciences.
facilities and the rise of multiply resistant bacteria, these